Vagusstoffe

Working with the vagus nerve attached to a frog's heart, Loewi showed that chemical substances are released when nerves are stimulated, particularly during synaptic transmission. It was later discovered that this "vagus material" was acetylcholine.
 Otto Loewi United States 1921 Vagusstoffe

Working with the vagus nerve attached to a frog's heart, Loewi showed that chemical substances are released when nerves are stimulated, particularly during synaptic transmission. It was later discovered that this "vagus material" was acetylcholine.