Cyanocobalamin structure

The detailed structure of cyanocobalamin was determined using X-ray diffraction and computational methods. This was the first direct use of a computer to solve a biochemical problem.
 Dorothy Mary Crowfoot Hodgkin England 1955 Cyanocobalamin structure

The detailed structure of cyanocobalamin was determined using X-ray diffraction and computational methods. This was the first direct use of a computer to solve a biochemical problem.